Radiesse in West Lafayette, IN

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Get Immediate Lift & Long-Term Rejuvenation

Searching for a filler that provides instant correction and stimulates your own collagen for long-lasting results?

Radiesse® is a unique dermal filler that does both. It immediately restores volume to smooth away wrinkles and folds, then works with your body to rebuild its natural collagen foundation. Serving Lafayette, West Lafayette, and the Greater Lafayette area - including Battle Ground, Dayton, and communities across Tippecanoe County achieve a refreshed, youthful look that lasts. Book a consultation today to discover the dual benefits of Radiesse.

What is Radiesse

Radiesse is a dermal filler made of Calcium Hydroxylapatite (CaHA) microspheres suspended in a smooth, aqueous gel carrier. This unique composition provides both immediate volume and long-term collagen stimulation.

Upon injection, the gel carrier instantly lifts and fills wrinkles and folds, providing immediate, visible results. Over the following weeks and months, the CaHA microspheres act as a scaffold, creating a structure that supports and stimulates the growth of your own natural collagen. This process, known as neocollagenesis, rebuilds the skin's underlying foundation, leading to improved skin quality, firmness, and elasticity.

Radiesse was first approved by the FDA in 2006 and has a long-standing safety record for treating moderate to severe facial wrinkles and folds, such as nasolabial folds. It is also FDA-approved for correcting volume loss in the back of the hands and for jawline contouring. The CaHA particles are biocompatible and are safely and naturally metabolized by the body over time, leaving behind only your own new collagen.

This dual-action mechanism makes Radiesse a versatile and effective treatment for both immediate correction and long-term, natural-looking rejuvenation. The results are clinically proven to last a year or more in many patients, making it a popular choice for those seeking durable and satisfying outcomes.

NIH‑Indexed Studies on Radiesse

A 2023 narrative review in the Aesthetic Surgery Journal highlighted that Radiesse (CaHA) treatment results in significant increases of collagen I and III, elastin, proteoglycans, and fibroblast populations. This regenerative process leads to tighter, brighter, more elastic, and more youthful-looking skin .


A 2024 study published in the Journal of Cosmetic Dermatology demonstrated that Radiesse(+) provides clinically meaningful and long-lasting improvements in jawline contour, with high patient satisfaction and a favorable safety profile observed through 60 weeks .

How It Works

Radiesse works in two distinct phases: immediate volumization from the gel carrier, followed by long-term collagen stimulation from the CaHA microspheres.

First, the smooth carboxymethylcellulose (CMC) gel provides instant lift and correction, filling in lost volume and smoothing out wrinkles and folds the moment it is injected. This allows you to see a noticeable improvement right away.

Next, the CaHA microspheres begin their work as a biostimulator. These tiny, spherical particles form a scaffold-like structure under the skin. Your body's natural response is to stimulate fibroblasts—the cells responsible for collagen production—to grow around this scaffold. This process leads to the gradual deposition of new, healthy Type I and Type III collagen, as well as elastin.

As the gel carrier is absorbed by the body over a few months, your own natural collagen takes its place, providing a durable, long-lasting structural support network. This not only maintains the initial volume correction but also improves skin quality, firmness, and elasticity from within for results that can last a year or more.

Benefits of Radiesse

Immediate & Long-Lasting Results

Provides instant volume correction and stimulates your own collagen for results that last a year or more.

Versatile Treatment Areas

Effectively treats nasolabial folds, marionette lines, chin wrinkles, and enhances jawline contour.

Dual-Action Rejuvenation

Acts as both a traditional filler and a collagen biostimulator for comprehensive facial enhancement.

High Safety Profile

FDA-approved with a long history of safe and effective use in aesthetic medicine.

Natural-Looking Volume

Restores lost volume and smooths wrinkles with a natural feel and appearance.

Why choose PURE Regenerative Medicine?

At Pure Regenerative Medicine, we believe your cosmetic treatments should be rooted in science, personalization, and whole-body wellness. Our approach is physician-led, ensuring the highest standards of safety and care.

Our team proudly serves Tippecanoe County with a modern approach to skincare. We utilize advanced diagnostics, including the Glimpse Skin Analyzer, to perform a detailed analysis of your skin. This helps us identify underlying concerns and create a truly personalized treatment plan. Whether you're new to injectables or a returning patient, our skilled injectors and compassionate staff are here to guide you.

How Radiesse Compares to Other Options

While hyaluronic acid (HA) fillers primarily offer volume, Radiesse provides both immediate volume and long-term collagen stimulation for more durable results.

Unlike biostimulators like Sculptra, which work gradually over several months, Radiesse offers the significant advantage of immediate visible correction. Compared to neurotoxins like Botox that target dynamic wrinkles caused by muscle movement, Radiesse is designed to fill static wrinkles and restore volume lost due to aging.

Full comparison here: Radiesse vs Sculptra - understanding the difference.

Radiesse Before & Afters

With Radiesse, you will see an immediate improvement in the treated areas due to the volumizing effect of the gel carrier. As your body begins to produce new collagen over the next 2-3 months, you will notice further improvements in skin quality, firmness, and contour. The final, long-lasting results are typically visible around 3 months post-treatment and can last for a year or more.

Ideal Candidates for Radiesse

Radiesse is an excellent option for healthy adults in their 30s to 60s who are experiencing moderate to severe facial wrinkles and volume loss and desire both immediate and long-lasting results.

Nasolabial Folds (Smile Lines)

Effectively smooths the deep creases that run from the nose to the corners of the mouth.

Marionette Lines

Reduces the lines that run downwards from the corners of the mouth, which can create a sad or angry appearance.

Pre-Jowl Folds

Helps to fill in the hollow areas on either side of the chin, restoring a smoother jawline.

Chin Wrinkles

Fills and smooths horizontal wrinkles on the chin for a more youthful look.

Jawline Contouring

Adds definition and structure to the jawline, creating a more sculpted and youthful profile.

Hand Rejuvenation

Restores lost volume to the back of the hands, minimizing the appearance of veins and tendons.

Contraindications include patients with a history of severe allergies, particularly to any of the components of Radiesse, or those who are pregnant or breastfeeding should not receive treatment. A full medical history will be reviewed during your consultation.

Your Initial Radiesse Consultation

At Pure Regenerative Medicine, your journey starts with a personalized consultation using the Glimpse Skin Analyzer. This professional tool allows for a detailed analysis of your skin health, volume loss, and unique goals for rejuvenation.

From there, we conduct a thorough review of your medical history to ensure the treatment is both safe and suitable for you. We then craft a custom treatment plan—including the amount of product and specific injection sites—to deliver the immediate and lasting results Radiesse is known for.

Preparing For Your Radiesse Session

To prepare for your appointment:

  • Avoid blood-thinning medications and supplements (like aspirin, ibuprofen, and fish oil) for 3–5 days.
  • Limit alcohol consumption for 24 hours before treatment.
  • Refrain from intense exercise on the day of your appointment.
  • Arrive with your skin clean and free of makeup.
  • Hydrate well to ensure your skin is in optimal condition.

These preparatory steps help ensure a smoother, more effective treatment session.

What to Expect from Your Radiesse Session

When you arrive at Pure Regenerative Medicine, you'll be welcomed into a calm, clinical treatment space. Your injector will review your treatment plan with you and cleanse the injection sites.

Using a fine needle or cannula, Radiesse is injected into the targeted areas. The product is often mixed with lidocaine to enhance comfort during the procedure. The injection process itself typically takes 15–30 minutes, depending on the areas being treated.

Your entire visit will last around 45-60 minutes.

After the procedure, you will receive post-care instructions. You can expect to see immediate results. Some temporary swelling, redness, or bruising at the injection sites is normal and usually subsides within a week. You can typically resume your normal activities right away.

How Long Do Results Last?

The results from Radiesse are long-lasting, with many patients enjoying their improvements for a year or even longer. The duration of effect is due to the combination of the initial gel filler and the new collagen that your body produces over time.

To maintain your results, a touch-up treatment is typically recommended after about 12-18 months, depending on your individual response and aesthetic goals.

Risks & Side Effects

Radiesse is FDA-approved and has a well-established safety profile. The most common side effects are mild, temporary, and related to the injection itself, such as swelling, bruising, redness, pain, and itching at the injection site. These typically resolve on their own within a few days to a week.

As with any dermal filler, there is a rare risk of more serious complications, such as the unintentional injection into a blood vessel. Choosing a skilled, experienced injector is crucial to minimizing these risks.

Your provider will discuss all potential risks and side effects with you during your consultation to ensure you are fully informed and comfortable with your treatment decision.

Cost of Radiesse in Lafayette, IN

The cost of Radiesse treatment is determined by the number of syringes needed to achieve your desired correction. During your consultation, we will provide a transparent, detailed cost estimate based on your unique anatomy and aesthetic goals.

At Pure Regenerative Medicine, we prioritize patient education and transparency. We invite you to contact our medical spa for more details on pricing and to learn about any available packages.

What to Expect from Your Radiesse Session

Ready to experience immediate lift and long-term rejuvenation with a trusted, physician-led medical spa? At Pure Regenerative Medicine in University Square, West Lafayette, our advanced technology and integrative wellness model ensure your experience is both safe and satisfying.

Serving Tippecanoe County and the surrounding areas, our experienced injectors are here to help you rediscover your confidence and vitality.

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